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HEPAXIMIN 550 Tablet
Therapeutic Class
Other Antibiotics
Indications
Acute infectious diarrhoea including travelers diarrhoea, Diarrhoea predominant Irritable Bowel Syndrome (IBS-D), Hepatic Encephalopathy (H.E.)
Chemical Composition
Each film-coated tablet contains Rifaximin BP 550 mg.
Packaging
Each box contains 10's tablets in alu-alu blister pack.
Dosage & Administration
Acute Infectious Diarrhoea including Travelers Diarrhoea: 200 mg three times daily for 3 days. Diarrhoea predominant Irritable Bowel Syndrome (IBS-D: 550 mg three times daily for 14 days. Hepatic Encephalopathy (H.E.): 550 mg twice daily
Contraindications
Hepaximin is contraindicated in patients with a hypersensitivity to Rifaximin, or any of the Rifamycin antimicrobial agents, or any of the components of this preparation
Side Effects
Common side effects are nausea, vomiting, abdominal pain, flatulence, headache and dizziness
Drug Interaction
Although In vitro studies demonstrated the potential of Rifaximin to interact with cytochrome P450 (CYP3A4), a clinical drug-drug interaction study demonstrated that Rifaximin did not significantly affect the pharmacokinetics of midazolam. An additional clinical drug-drug interaction study showed no effect of Rifaximin on the presystemic metabolism of an oral contraceptive containing ethinyl estradiol and norgestimate. Therefore, clinical interactions with drugs metabolized by human cytochrome P450 isozymes are not expected.