Laxatives, Purgatives

1. Constipation (chronic constipation): In every case of chronic constipation, initial treatment should consist of a diet rich in fiber (vegetables, salads, fruits, supplements of linseeds, wheat germ etc.) a generous amount of liquids and much physical exercise. Avolac is only to be taken when these measures prove insufficient.2. Intestinal flora disturbances: In damage to intestinal flora, following therapy with broad-spectrum antibiotics, gall bladder diseases, and intestinal diseases (colitis, diverticulosis, megacolon, etc.)3. Increased blood ammonia levels (hyperammonemia in hepatopathy, portal-systemic encephalopathy, precoma, coma).4. Diseases of the gums and the periodontal apparatus (periodontosis, bleeding from the gums, inflammation, dystrophy).

Avolac Solution: Avolac (Lactulose) is an oral solution containing Lactulose USP 3.35 g / 5 ml.

100 ml / Bot

Dosage should be followed accurately unless otherwise specified. 1. In constipation (chronic constipation): Due to the fact that every organism responds differently to Avolac, each patient must determine his/her own optimal dose in the course of time. Adults: Initially 3-6 tea-spoons daily; In long-term therapy 1.5-6 tea-spoons daily, Children up to 14 years: Initially 3 tea-spoons daily; in long-term therapy 1-2 tea-spoons daily, Infants and toddlers: initially 1-2 tea-spoons daily; in long-term therapy 1 tea-spoon daily. With Avolac a prompt laxative effect may be achieved by drinking a mixture of 3-9 tea-spoons in 1/8-1/4 liter water, coffee, tea, fruit juice, or milk on an empty stomach after getting up in the morning. Normally, defecation takes place approximately 2 hours later in the form of a fluid pulpy mass (increased defecation reflex). 2. In damaged intestinal flora (e.g. following long-term antibiotic treatment): Adults: 1-2 tea-spoon daily, Children: 1 tea-spoon daily. 3. For reduction of blood ammonia level (In hepatopathy): A maximum of 60-100 g Lactulose daily, that is. 18-30 tea-spoons. 4. In precoma: A maximum of 100 g Lactulose daily, that is 30 tea-spoons Avolac spread over the course of the day. 5. Diseases of the gums and the parodontic apparatus (paradontopathy): Adults : 3-6 tea-spoons daily.

Hypersensitivity to either galactose and/ or lactose, galactose-free diet. Gastro-cardiac symptom complex (heart problems stemming from the gastro-intestinal tract), suspected intestinal obstruction.

Occasionally flatulence can occur at the beginning of treatment, this is rapidly eliminated by reducing the dose and/ or taking the daily dose in several smaller individual portions spread over the course of the day. Overdosage can result in diarrhoea. In abuse: loss of electrolytes (primarilty Potassium):

The glycosidic effect of cardiac glycosides can be intensified by potassium deficiency in abuse.

Aristopharma Ltd., Bangladesh.