Proton Pump Inhibitors

Gastric ulcer (GU), Peptic ulcer disease (PUD), Maintenance of healing of erosive or ulcerative GERD, Healing of erosive and ulcerative GERD, Healing of duodenal ulcers. Treatment of pathological hypersecretory conditions (Zollinger-Ellison syndrome) Helicobacter pylori eradication to reduce risk of duodenal ulcer recurrence.

Each enteric coated tablet contains Rabeprazole Sodium 20 mg

10 x 10's / Box

Tablets should be swallowed whole and should not be crushed, split or chewed. Rabeprazole can be taken with or without meals since food has little effect on its absorption. For healing ulcerating GERD, the recommended dose for adults is 20 mg daily for 4-8 weeks. Heartburn due to GERD is treated with 20 mg daily for 4 weeks and an additional 4 weeks if symptoms do not resolve. Ulcers are treated with 20 mg daily for 4 weeks. For the management of Zollinger-Ellison Syndrome, the starting dose for adults is 60mg daily.

Hypersensitivity to rabeprazole, substituted benzimidazoles or any of components of its pharmaceutical forms. Pregnancy: FDA Pregnancy Ratings: B Lactation: Thomson Lactation Ratings: Infant risk cannot be ruled out.

Anxiety, arthralgia, asthenia, constipation, diarrhea, dry mouth, erythema, granulocytopenia headache,increased or decreased appetite, insomnia, leukocytopenia, meteorism, muscle.

Rabeprazole decreases the concentration of ketoconazole in the plasma (in 33%), increases the concentration of digoxin (in 22%), and does not interact with liquid antacids. Rabeprazole is compatible with any medicine metabolized CYP450

Rhydburg Pharmaceuticals Ltd.,India