Antacids, Antireflux Agents & Antiulcerants

Healing of Erosive or Ulcerative GERD. Maintenance of Healing of Erosive or Ulcerative GERD. Treatment of Symptomatic GERD. Healing of Duodenal Ulcers. Helicobacter pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence.Treatment of Pathological Hypersecretory Conditions. Including Zollinger-Ellison Syndrome

Rabaris Tablet: Each enteric coated tablet contains Rabeprazole Sodium INN 20 mg.

5 x 10's / Box

Rabaris tablet should be swallowed whole. Rabaris tablet can be taken with or without food.

Rabeprazole is contraindicated in patients with known hypersensitivity to Rabeprazole or to any component of the formulation.

Administration of Rabeprazole to patients with mild to moderate liver impairment results in increased exposure and decreased elimination. Caution should be exercised in patients with severe hepatic impairment.

Rabeprazole tablets are generally well tolerated. The observed undesirable effects have been generally mild/moderate and transient in nature. The most common adverse events are headache, diarrhea and nausea. The less common adverse effects are abdominal pain, asthenia, flatulence, rash, dry mouth etc.

Rabeprazole like other PPIs is metabolized through Cytochrome P450 drug metabolizing enzyme system. But Rabeprazole does not have clinically significant interaction with other drugs metabolized by CYP P450 system, such as warfarin, theophylline, diazepam and phenytoin.Rabeprazole inhibits gastric acid secretion and may interfere with absorption of drugs where gastric pH is an important determinant of bioavailability e.g. ketoconazole, iron salts and digoxin.In studies no interaction with liquid antacid or foods was observed.

Aristopharma Ltd., Bangladesh.