Proton Pump Inhibitors plus Anti-emetics

Antacids, Antireflux Agents & Antiulcerants / GIT Regulators, Antiflatulents & Anti-Inflammatories.

Each hard gelatin capsule contains Pantoprazole Sodium Sesquihydrate BP eq. to Pantoprazole 40 mg (as enteric coated Pellets), Domperidone BP 30 mg. ( as sustained release pellets)

10 x 10's per bo

Once or Twice capsule once daily or as directed by the physician.

Pantoprazole is contraindicated in heptic impairment; hypersensitivity. Domperidone is contraindicated in the history of hypersensitivity to dimenhydrinate or related compounds.

Nausea, drowsiness, flatulence and dry mouth

Because of profound and long lasting inhibition of gastric acid secretion, pantoprazole may reduce the absorption of drugs with a gastric pH dependent bioavailability, e.g some azole antifungals as ketoconazole, itraconazole, posaconazole Itraconazole and ketoconazole, both used to treat fungal infections increase the plasma concentration of domperidone. Erythromycin and other macrolide antibiotics inhibit the metabolism of domperidone (in-vitro) thus increasing the concentration of domperidone and potential side effects of the drug.

Rhydburg Pharmaceuticals Ltd.,India