Topical Antifungals

Zarin is indicated for the topical treatment of skin infections due to susceptible fungi (dermatophytes and yeasts) such as tinea pedis (athlete's foot), tinea cruis, tinea corporis (ringworm), tinea versicolor (white spots), and candidiasis

Contains Miconazole Nitrate 2% w/w in a non greasy, non-staining cream basis. Benzoic Acid 0.15% w/w as preservative.

15 g / Tube

Apply a thin layer of Zarin sufficient to cover the affected areas and rub well into the skin until the cream has been completely absorbed. The cream should be applied once or twice a day, in the morning and evening, and continued without interruption until the symptoms have been completely disappeared (usually 2 to 5 weeks, depending on the infecting organism and the site of infection).

Zarin is contraindicated in patients known to be hypersensitive to imidazole antifungal agents or any components of the medication

Discontinue treatment if sensitisation or irritation occurs during use. DO NOT USE IN THE EYES. It is advisable to consult a doctor if no improvement is observed in 4 weeks in the case of 'athlete's foot' or 2 weeks in 'jock itch: In patients on warfarin, caution should be exercised and the anticoagulant effect should be monitored (see Interactions).

Zarin is usually well tolerated. However, local irritation and sensitivity reactions may occasionally occur.

Miconazole administered systemically is known to inhibit CYP2C9 enzyme system. Due to the limited systemic availability after topical application, clinically relevant interactions occur very rarely. In patients on warfarin which is subjected to metabolism by CYP2C9, caution should be exercised and the anticoagulant effect should be monitored (see Warnings and Precautions).

Xepa-Soul Pattinson.,Malaysia